Wall Street Journalのインスタグラム(wsj) - 10月26日 09時00分


When Leslie Hendeles walked into his neighborhood drugstore last week and learned that a common cold medicine was being pulled off the shelves, he was stunned. The news affirmed a decadeslong quest to steer consumers away from a drug that he long-believed didn’t work.⁠

Hendeles, a retired professor, with his friend, fellow pharmacist and University of Florida professor Randy Hatton, have spent nearly 20 years following the science of phenylephrine, an ingredient in more than 200 over-the-counter decongestants.⁠

Last month, following a petition from Hatton and Hendeles, an advisory panel to the Food and Drug Administration weighed studies examining oral phenylephrine’s power to unblock sinuses and clear stuffy noses, and unanimously determined that it wasn’t effective.⁠

Last week CVS, one of the nation’s biggest pharmacies, told WSJ that certain medicines that list phenylephrine as their only active ingredient were being pulled from shelves for good.⁠

“Pharmacists were telling us, this doesn’t work,” Hatton said. Over two decades the duo amassed evidence that backed up their conviction, and drew attention to the issue from lawmakers, health agencies, pharmacies and their customers.⁠

Approved for use nearly a century ago, phenylephrine is listed as an ingredient in pills, syrups and liquids such as Advil Sinus Congestion & Pain, Flonase Headache & Allergy Relief, and DayQuil Cold & Flu.⁠

But studies over the years have shown that it is not more effective to clear nasal congestion than a placebo when taken orally. Scientists believe that is partly because almost all of it is inactivated in the gut and liver before it reaches the bloodstream.⁠

Read more at the link in our bio.⁠

📷: @malcjax for @wsjphotos


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